胃肠道基质肿瘤

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胃肠道基质肿瘤
分类系统及外部资源

部胃肠道基质肿瘤之组织病理影像(以苏木精曙红着色显示)
DiseasesDB 33849
MeSH D046152
GIST内视镜影像位于胃的底部,见于后屈(retroflexion)部
同样的内视镜前端GIST影像,显示出肿瘤的高度凝块

胃肠道基质肿瘤(Gastrointestinal stromal tumor,简称GIST)是一种肠道基质细胞病变,源由于身体的一个名为C-Kit(CD117)的基因出现突变,引致肠道壁的神经系统细胞演变成为肿瘤细胞。GIST的影响范围不限定于肠道,而可以遍及食道、胃、小肠大肠直肠;而随着GIST在消化道的不同部位发生,病者亦会出现不同的病征[1]

目录

注释

  1. 朱建华,(2007年),〈肠话短说:认识胃肠道基质肿瘤〉,《都市日报》2007年11月23日号,P.34 健康。

参考文献

  1. De Silva MV, Reid R. Gastrointestinal stromal tumors (GIST): c-kit mutations, CD117 expression, differential diagnosis and targeted cancer therapy with imatinib. Pathol Oncol Res 2003;9:13-9. PMID 12704441.
  2. Kitamura Y, Hirota S, Nishida T. Gastrointestinal stromal tumors (GIST): a model for molecule-based diagnosis and treatment of solid tumors. Cancer Sci 2003:94:315-20. PMID 12824897.
  3. Miettinen M, Lasota J (2006). "Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis". Arch Pathol Lab Med 130 (10): 1466-78. PMID 17090188.

外部连结

医学研究连结

病患导向之网站

  • GIST Support International, An international organization for the support of GIST patients, families, and friends. Includes detailed information from some of the foremost experts on GIST, links to research, treatment options, GIST registry, adult and pediatric listservs, and affiliated GSI-Wiki.
  • Life Raft Group International GIST Advocacy Organization. Provides support to patients & families, through information, education, and innovative research.
  • GIST Info Patient links, includes information on new clinical trials and research
  • American Cancer Society Patient Guide to GIST tumors.
  • GIST 胃肠不可Blog

参考来源

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